Doña Aurora High School was established in 1949 in a Spanish building across the public market in Barrio Guitnangbayan in San Mateo. It was named Doña Aurora in 1950, in memory of Doña Aurora Quezon, former First Lady of the Philippines, a social worker and an educator. In 1954, the school transferred to its current site behind the Nuestra Señora de Aranzazu Church.

In 1995, Doña Aurora High School was renamed Roosevelt College San Mateo as it has to have the same name as the other units in the Roosevelt College System. Over the years, the school underwent massive infrastructure improvements.  It offers a rich curriculum challenging the intellectual, social, and physical talents of its students.

Mrs. Norita L. Lachenal is the current Directress of the school, which marked its 61st Founding Anniversary in 2011.

The School Directress supervises the implementation of the Roosevelt College System’s policies so that all constituents including students, parents, academic and non-academic personnel, as well as alumni are united in achieving the school’s vision, mission, and goals.